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Manchester United manager Alex Ferguson confirmed on Monday that Phil Jones will miss the conclusion of his side's Champions League last 16 tie with Real Madrid due to injury.
The Premier League leaders held Madrid to a 1-1 draw in the Spanish capital three weeks ago, with Jones helping to shackle former United star Cristiano Ronaldo from a defensive midfield role.
However, the England international injured his ankle in an FA Cup game against Reading five days later and Ferguson said he would not be able to face Jose Mourinho's side in the second leg at Old Trafford on Tuesday.
"Phil Jones is not fit and won't be fit for tomorrow (Tuesday)," Ferguson said.
"His performance over there was excellent and it's a miss, but it's not something we can't manage. We've got options and hopefully we'll get that right."