Syrian President Bashar al-Assad warned in comments broadcast Friday that the fall of his regime would produce a "domino effect" that would destabilise the region "for many years".
"The whole world knows that if Syria is partitioned, or if terrorist forces take control of the country, there will be direct contagion of the surrounding countries," Assad said in an interview with two Turkish media outlets.
"Then there would be a domino effect on countries perhaps far from the Middle East, to the west, east, north and south. This would mean instability for many years, even decades," he said.
Video of the interview, conducted earlier in the week, was posted on the Syrian presidency's Facebook page on Friday evening.
In the interview Assad also slammed Turkish Prime Minister Recep Tayyip Erdogan and accused Ankara of complicity in the deaths of Syrians.
In excerpts posted earlier this week, Assad lashed out at the Arab League and its decision to hand Syria's seat to the opposition.
"The Arab League lacks legitimacy. It's a League that represents the Arab states, not the Arab people, so it can't grant or retract legitimacy."
"Real legitimacy is not accorded by organisations or foreign officials or other country... legitimacy is that which is granted by the people," Assad said.
The interview, with Turkey's Ulusal television and Aydinlik newspaper, focused extensively on Syria's ties with Ankara, which has backed the two-year uprising against his regime.
In extracts published on Wednesday, Assad accused Erdogan of not having said "a single word of truth since the beginning of the crisis in Syria."
"The fire in Syria will spread to Turkey, unfortunately (Erdogan) doesn't see this reality," Assad added in the footage released on Friday.
"Erdogan is working with Israel to destroy Syria... but the Syrian state has not fallen and the Syrian people have resisted," he said, accusing the Turkish government of "contributing directly to the killing of the Syrian people."
"We cannot allow idiot, immature leaders to destroy relations" between the Turks and the Arabs, Assad said.
Damascus has regularly accused Ankara of financing, training and arming rebels fighting troops loyal to Assad. The United Nations says Turkey currently hosts more than 260,000 Syrian refugees.
Assad, who describes opponents of his regime as "terrorists" said he remained open to dialogue but without foreign interference.
"The dialogue must be intra-Syrian, without foreign interference. That is the only red line. This country is for all Syrians, they can discuss what they want," he said.
Syrian rebel chief Ahmed Moaz al-Khatib in January suggested he would be open to dialogue with representatives of the regime, but said that subsequent government attacks throughout Syria effectively closed the doors to talks.
The UN says more than 70,000 people have been killed in a spiralling war that broke out in March 2011 after the army unleashed a crackdown on a peaceful revolt which morphed into an armed uprising.