Chinese shares fell 1.63 percent in early trading on Monday after a long holiday on worries over an outbreak of bird flu and losses in US stocks last week, dealers said.
The benchmark Shanghai Composite Index slid 36.17 points to 2,189.13. The market was closed Thursday and Friday.
Hotel and tourism shares led the declines on worries their business would be affected after China confirmed 21 cases of the H7N9 strain of avian influenza in its developed eastern region. Six people have died, including four in the commercial city of Shanghai which has recorded 10 cases of the disease.