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* Football stadium case a flashpoint for unrest
* Court to give final ruling on death sentences
* Thousands take to streets of Mediterranean city (Adds new security forces chief)
By Yusri Mohamed
PORT SAID, Egypt, March 8 (Reuters) - Thousands of Egyptians packed the streets of the Suez Canal city of Port Said on Friday in protest at the deaths of local people in clashes with police and before a court decision in a contentious football riot case.
Violence has flared in Port Said since January, with protests over death sentences given to 21 local people in connection with a stadium riot in which more than 70 died.
The football stadium deaths occurred in February last year at the end of a match between Cairo's Al Ahly and al-Masry, the local side, and have been a flashpoint for protests across Egypt.
Spectators were crushed when panicked crowds tried to escape from the stadium after a pitch invasion by supporters of al-Masry. Others fell or were thrown from terraces.
The confirmation of the sentences of those accused of involvement in the disaster is expected on Saturday in Cairo, and could provoke more unrest in Port Said and the capital.
A protester in Port Said died of a bullet wound to the head on Friday which he sustained in clashes with police earlier in the week, a medical source said. Another protester died during the night after violence on Thursday.
Protesters holding flags chanted "With our blood we will redeem you, Port Said!" and "The people want to bring down the regime", the signature chant of the demonstrators who ended Hosni Mubarak's 30-year rule in 2011.
Egypt's revolution eventually installed an elected Islamist-led government which is still struggling to assert its authority, restore order and revive the economy.
The protesters also called for the departure of police forces and shouted slogans against President Mohamed Mursi.
At least eight people have been killed in this week's protests in the city, including three policemen.
The army formed a security cordon around the central security directorate building in Port Said and local government offices. The officers are there to protect the area and stop bloodshed but not to police the people, Major General Ahmed Wasfi said.
Egypt's security situation has deteriorated and police officers have been striking across the country, saying they do not have enough weapons and officers to deal with the unrest.
On Friday the Interior Minister replaced Maged Nouh, the powerful head of country's central security forces, with Ashraf Abdullah, the state news agency MENA said without giving a reason.
Authorities tightened security in Port Said and in Cairo before the final court ruling and will deploy 2,000 police around the police academy in Cairo, where the football stadium hearing will be held, MENA reported, citing a source in the Interior Ministry. Defendants will be transported in armoured vehicles.
In Cairo, there were skirmishes between dozens of protesters and police on a Nile bridge near Tahrir Square, the heart of the 2011 uprising, while in the second city of Alexandria hundreds of people protested outside local government headquarters.
Hundreds of police refused to work for a third day at a base outside Ismailia, at the half-way point of the canal and where the Suez Canal Authority has its headquarters, demanding more arms after several of their colleagues were killed in recent clashes.
Thousands of Egyptian riot police and conscripts also went on strike on Wednesday to demand the resignation of the Interior Minister, saying he is too close to the country's Islamist leadership, security sources said.
The Interior Ministry has been at the forefront of clashes involving the mainly young protesters, who complain that Mursi has done little to reform the police since the revolution. (Additoinal reporting by Omar Fahmy in Cairo and; Abdel Rahman Yousef in Alexandria, Writing by Sylvia Westall; Editing by Michael Roddy and David Stamp)