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OLB Parys Haralson, who was acquired in a trade on Aug. 26, could start Sunday with Junior Galette and Martez Wilson coming off injuries that sidelined them for the entire preseason schedule.
ILB Jonathan Vilma has been sidelined since Aug. 15 after having his knee scoped and it's not known when he'll return to the lineup.
RG Jahri Evans, a fourth-time All-Pro pick, missed the third preseason game and some practices for an undisclosed reason and his status for Sunday's game is not known.
G Eric Olsen (knee) was placed on reserve/injured by the Saints Saturday.
CB Patrick Robinson, a starter last season, could be on the field in the dime package after recovering from arthroscopic knee surgery in June.
OLB Junior Galette missed all four preseason games with a lower leg injury and his return is unknown.
S Kenny Vaccaro, the team's first-round draft pick, will likely be the starting nickel back for the season opener after a strong training camp.