QB Peyton Manning's return to Indianapolis saw mixed results. He finished with 386 yards and three touchdown passes, but a fourth-quarter interception under pressure from Erik Walden was costly, and his fumble on a second-quarter sack bounced out of bounds for a safety.
WR Wes Welker was held without a touchdown for the first time since joining the Broncos, but finished with 96 yards on seven catches.
LB Wesley Woodyard was inactive for a second consecutive game after suffering a neck injury against Dallas on Oct. 6. Woodyard practiced on a limited basis last week and is considered "day to day" by coach John Fox.
DE Robert Ayers returned after missing Week 6 because of a shoulder injury. He played 21 snaps against the Colts, with a reduced workload resulting from the return of Von Miller.
RG Chris Kuper made his first start of the season Sunday. He played every snap, by far his most extensive work since having ankle surgery this offseason, and gave up a sack.
C J.D. Walton is one week into the three-week window of practice during which the Broncos must decide whether to keep him on physically unable to perform or restore him to the 53-man roster. Walton was on PUP list following a second surgery to repair a fractured ankle, but began practicing Oct. 16.
OT Orlando Franklin missed the game with sprains in his left knee and ankle, suffered on Oct. 13 against Jacksonville. He did not practice at all last week and might be held out this week, with the Broncos' bye coming the week after that.
LB/DE Von Miller did not record a sack in his first game back from a six-game suspension, but he hit Colts QB Andrew Luck twice and finished with one tackle for a loss. Miller's durability appeared unaffected, and he played all but four snaps.
G Louis Vasquez made his first NFL start at right tackle Sunday in place of the injured Orlando Franklin and didn't allow any sacks or hits of quarterback Peyton Manning.
CB Champ Bailey aggravated his sprained left foot in the second quarter against the Colts and left the game. He underwent what coach John Fox called "a battery of tests" and is considered "week to week." Bailey missed the first five regular-season games with the injury, which he suffered in a preseason loss at Seattle Aug. 17.
RB Ronnie Hillman's fumble at the Indianapolis 3-yard-line with 3:15 remaining effectively ended the Broncos' hopes of a comeback from a 19-point deficit. Hillman has fumbled twice in the regular season, and dating back to the preseason, has fumbled four times in 79 touches.