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The migrants were detained in separate operations in the southern states of Oaxaca and Chiapas and two suspected traffickers were taken into custody.
The 48 Guatemalans, 28 Salvadorans and five Hondurans were "apparently trying to reach the United States," according to an official statement.
The group included eight minors.
Three women and 24 men were discovered inside a cattle truck that was traveling northbound through Oaxaca at night with its headlights off.
In neighboring Chiapas, police detected a total of 54 migrants aboard two buses and a private vehicle.
Several hundred thousand Central Americans migrants cross Mexico every year trying to reach the United States. The arduous trek is made still more dangerous by criminals and corrupt Mexican officials who prey on the migrants.